FRANKLINIZA'TION

\fɹˌaŋklɪnɪzˈaʃən], \fɹˌaŋklɪnɪzˈaʃən], \f_ɹ_ˌa_ŋ_k_l_ɪ_n_ɪ_z_ˈa_ʃ_ə_n]\

Definitions of FRANKLINIZA'TION

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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