VERRUCOUS CARCINOMA
\vɛɹˈuːkəs kˌɑːsɪnˈə͡ʊmə], \vɛɹˈuːkəs kˌɑːsɪnˈəʊmə], \v_ɛ_ɹ_ˈuː_k_ə_s k_ˌɑː_s_ɪ_n_ˈəʊ_m_ə]\
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A variant of well-differentiated epidermoid carcinoma that is most common in the oral cavity, but also occurs in the larynx, nasal cavity, esophagus, penis, anorectal region, vulva, vagina, uterine cervix, and skin, especially on the sole of the foot. Most intraoral cases occur in elderly male abusers of smokeless tobacco. The treatment is surgical resection. Radiotherapy is not indicated, as up to 30% treated with radiation become highly aggressive within six months. (Segen, Dictionary of Modern Medicine, 1992)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.