VARICELLA ENCEPHALITIDES
\vˌaɹa͡ɪsˈɛləɹ ɛnsˈɛfɐlˌɪta͡ɪdz], \vˌaɹaɪsˈɛləɹ ɛnsˈɛfɐlˌɪtaɪdz], \v_ˌa_ɹ_aɪ_s_ˈɛ_l_ə_ɹ ɛ_n_s_ˈɛ_f_ɐ_l_ˌɪ_t_aɪ_d_z]\
Sort: Oldest first
-
Inflammation of brain tissue caused by infection with the varicella-zoster virus (HERPESVIRUS 3, HUMAN). This condition is associated with immunocompromised states, including the ACQUIRED IMMUNODEFICIENCY SYNDROME. Pathologically, the virus tends to induce a vasculopathy and infect oligodendrocytes and ependymal cells, leading to CEREBRAL INFARCTION, multifocal regions of demyelination, and periventricular necrosis. Manifestations of varicella encephalitis usually occur 5-7 days after onset of HERPES ZOSTER and include HEADACHE; VOMITING; lethargy; focal neurologic deficits; FEVER; and COMA. (From Joynt, Clinical Neurology, 1996, Ch 26, pp29-32; Hum Pathol 1996 Sep;27 (9):927-38)
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.