MALOT'S REACTION

\mˈalɒts ɹɪˈakʃən], \mˈalɒts ɹɪˈakʃən], \m_ˈa_l_ɒ_t_s ɹ_ɪ__ˈa_k_ʃ_ə_n]\

Definitions of MALOT'S REACTION

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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