GANGLIONEUROMA
\ɡˌaŋɡlɪˌə͡ʊnjuːɹˈə͡ʊmə], \ɡˌaŋɡlɪˌəʊnjuːɹˈəʊmə], \ɡ_ˌa_ŋ_ɡ_l_ɪ__ˌəʊ_n_j_uː_ɹ_ˈəʊ_m_ə]\
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A benign neoplasm that usually arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. The tumor may present clinically with HORNER SYNDROME or diarrhea due to ectopic production of vasoactive intestinal peptide. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p966)
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