DIAMOND BLACKFAN ANEMIA
\dˈa͡ɪ͡əmənd blˈakfən ɐnˈiːmi͡ə], \dˈaɪəmənd blˈakfən ɐnˈiːmiə], \d_ˈaɪə_m_ə_n_d b_l_ˈa_k_f_ə_n ɐ_n_ˈiː_m_iə]\
Sort: Oldest first
-
A rare congenital hypoplastic anemia that usually presents early in infancy. The disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (Curr Opin Hematol 2000 Mar;7 (2):85-94)
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.