SPINE OF DARWIN

\spˈa͡ɪn ɒv dˈɑːwɪn], \spˈa‍ɪn ɒv dˈɑːwɪn], \s_p_ˈaɪ_n ɒ_v d_ˈɑː_w_ɪ_n]\

Definitions of SPINE OF DARWIN

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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