NEPHRALGIC

\nɛfɹˈald͡ʒɪk], \nɛfɹˈald‍ʒɪk], \n_ɛ_f_ɹ_ˈa_l_dʒ_ɪ_k]\
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1900 - A dictionary of medicine and the allied sciences
By Alexander Duane

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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