NEPHRALGIA ARENOSA

\nɛfɹˈald͡ʒəɹ ˌaɹɪnˈə͡ʊsə], \nɛfɹˈald‍ʒəɹ ˌaɹɪnˈə‍ʊsə], \n_ɛ_f_ɹ_ˈa_l_dʒ_ə_ɹ ˌa_ɹ_ɪ_n_ˈəʊ_s_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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