KIT PROTO ONCOGENE PROTEIN
\kˈɪt pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːn pɹˈə͡ʊtiːn], \kˈɪt pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːn pɹˈəʊtiːn], \k_ˈɪ_t p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n p_ɹ_ˈəʊ_t_iː_n]\
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A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. EC 2.7.11.-.
By DataStellar Co., Ltd
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