POISONING, 1 METHYL 4 PHENYL 1,2,3,6 TETRAHYDROPYRIDINE
\pˈɔ͡ɪzənɪŋ], \pˈɔɪzənɪŋ], \p_ˈɔɪ_z_ə_n_ɪ_ŋ]\
Definitions of POISONING, 1 METHYL 4 PHENYL 1,2,3,6 TETRAHYDROPYRIDINE
Sort: Oldest first
-
A condition caused by the neurotoxin 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. MPTP causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36 (2):250-8)
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
- poisonberry
- poisoned
- poisoned wound
- poisoner
- poisoning
- Poisoning, 1 Methyl 4 phenyl 1,2,3,6 tetrahydropyridine
- poisoning, arsenic, nervous system
- poisoning, heavy metals, nervous system
- poisoning, lead, nervous system
- poisoning, lead, nervous system, adult
- poisoning, lead, nervous system, childhood