PERICARDIUM INTERNUM

\pˌɛɹɪkˈɑːdi͡əm ˌɪntənˈʌm], \pˌɛɹɪkˈɑːdi‍əm ˌɪntənˈʌm], \p_ˌɛ_ɹ_ɪ_k_ˈɑː_d_iə_m ˌɪ_n_t_ə_n_ˈʌ_m]\

Definitions of PERICARDIUM INTERNUM

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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