PERFORATED SPACE

\pˈɜːfəɹˌe͡ɪtɪd spˈe͡ɪs], \pˈɜːfəɹˌe‍ɪtɪd spˈe‍ɪs], \p_ˈɜː_f_ə_ɹ_ˌeɪ_t_ɪ_d s_p_ˈeɪ_s]\
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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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