PACINIAN BODIES

\pasˈɪni͡ən bˈɒdɪz], \pasˈɪni‍ən bˈɒdɪz], \p_a_s_ˈɪ_n_iə_n b_ˈɒ_d_ɪ_z]\

Definitions of PACINIAN BODIES

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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