NEPHRITOGENIC ANTIGEN

\nˌɛfɹɪtə͡ʊd͡ʒˈɛnɪk ˈantɪd͡ʒˌɛn], \nˌɛfɹɪtə‍ʊd‍ʒˈɛnɪk ˈantɪd‍ʒˌɛn], \n_ˌɛ_f_ɹ_ɪ_t_əʊ_dʒ_ˈɛ_n_ɪ_k ˈa_n_t_ɪ_dʒ_ˌɛ_n]\

Definitions of NEPHRITOGENIC ANTIGEN

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2010 - Medical Dictionary Database
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  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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