LEVAMISOLE HYDROCHLORIDE
\lˈɛvɐmˌɪsə͡ʊl hˈa͡ɪdɹəklˌɔːɹa͡ɪd], \lˈɛvɐmˌɪsəʊl hˈaɪdɹəklˌɔːɹaɪd], \l_ˈɛ_v_ɐ_m_ˌɪ_s_əʊ_l h_ˈaɪ_d_ɹ_ə_k_l_ˌɔː_ɹ_aɪ_d]\
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An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
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