GROWTH ASSOCIATED PROTEIN 43
\ɡɹˈə͡ʊθ ɐsˈə͡ʊsɪˌe͡ɪtɪd pɹˈə͡ʊtiːn fˈɔːtiθɹˈiː], \ɡɹˈəʊθ ɐsˈəʊsɪˌeɪtɪd pɹˈəʊtiːn fˈɔːtiθɹˈiː], \ɡ_ɹ_ˈəʊ_θ ɐ_s_ˈəʊ_s_ɪ__ˌeɪ_t_ɪ_d p_ɹ_ˈəʊ_t_iː_n f_ˈɔː_t_i_θ_ɹ_ˈiː]\
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A nervous tissue specific protein which is highly expressed in neurons during development and nerve regeneration. It has been implicated in neurite outgrowth, long-term potentiation, signal transduction, and neurotransmitter release. (From Neurotoxicology 1994;15 (1):41-7) It is also a substrate of PROTEIN KINASE C.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
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