GROSSICH'S METHOD

\ɡɹˈə͡ʊsɪt͡ʃɪz mˈɛθəd], \ɡɹˈə‍ʊsɪt‍ʃɪz mˈɛθəd], \ɡ_ɹ_ˈəʊ_s_ɪ_tʃ_ɪ_z m_ˈɛ_θ_ə_d]\

Definitions of GROSSICH'S METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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