GAP43 PROTEIN
\d͡ʒˌiːˌe͡ɪpˈiː fˈɔːtiθɹˈiː pɹˈə͡ʊtiːn], \dʒˌiːˌeɪpˈiː fˈɔːtiθɹˈiː pɹˈəʊtiːn], \dʒ_ˌiː__ˌeɪ_p_ˈiː f_ˈɔː_t_i_θ_ɹ_ˈiː p_ɹ_ˈəʊ_t_iː_n]\
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A nervous tissue specific protein which is highly expressed in neurons during development and nerve regeneration. It has been implicated in neurite outgrowth, long-term potentiation, signal transduction, and neurotransmitter release. (From Neurotoxicology 1994;15 (1):41-7) It is also a substrate of PROTEIN KINASE C.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.