FRAMESHIFT MUTATIONS
\fɹˈe͡ɪmʃɪft mjuːtˈe͡ɪʃənz], \fɹˈeɪmʃɪft mjuːtˈeɪʃənz], \f_ɹ_ˈeɪ_m_ʃ_ɪ_f_t m_j_uː_t_ˈeɪ_ʃ_ə_n_z]\
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A type of mutation in which a number of nucleotides not divisible by three is deleted from or inserted into a coding sequence, thereby causing an alteration in the reading frame of the entire sequence downstream of the mutation. These mutations may be induced by certain types of mutagens or may occur spontaneously.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.