FILIX MAS
\fˈɪlɪks mˈas], \fˈɪlɪks mˈas], \f_ˈɪ_l_ɪ_k_s m_ˈa_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.