ELKANAH SETTLE

\ˈɛlkanə sˈɛtə͡l], \ˈɛlkanə sˈɛtə‍l], \ˈɛ_l_k_a_n_ə s_ˈɛ_t_əl]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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