ELECTROPHORETIC MOBILITY SHIFT ASSAY
\ɪlˌɛktɹə͡ʊfɔːɹˈɛtɪk mə͡ʊbˈɪlɪti ʃˈɪft ɐsˈe͡ɪ], \ɪlˌɛktɹəʊfɔːɹˈɛtɪk məʊbˈɪlɪti ʃˈɪft ɐsˈeɪ], \ɪ_l_ˌɛ_k_t_ɹ_əʊ_f_ɔː_ɹ_ˈɛ_t_ɪ_k m_əʊ_b_ˈɪ_l_ɪ_t_i ʃ_ˈɪ_f_t ɐ_s_ˈeɪ]\
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An electrophoretic technique employed to assay for binding of one compound to another. Typically one compound is labeled to follow its mobility during electrophoresis. The movement of the labeled compound through the electrophoretic medium will be retarded if it is bound by the other.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.