ECSTROPHY

\ˈɛkstɹəfi], \ˈɛkstɹəfi], \ˈɛ_k_s_t_ɹ_ə_f_i]\
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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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