COUNTER-IRRITANT

\kˈa͡ʊntəɹˈɪɹɪtənt], \kˈa‍ʊntəɹˈɪɹɪtənt], \k_ˈaʊ_n_t_ə_ɹ_ˈɪ_ɹ_ɪ_t_ə_n_t]\
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  • See Counter-irritation- c. Granvilles, (Lotion,) Granvilles Counter-irritant.
1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison
 
1871 - The Cabinet Dictionary of the English Language

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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