CARDUUS NUTANS

\kˈɑːdʌəs njˈuːtənz], \kˈɑːdʌəs njˈuːtənz], \k_ˈɑː_d_ʌ_ə_s n_j_ˈuː_t_ə_n_z]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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