BRECKENRIDGE, WILLIAM C. P.
\bɹˈɛkənɹˌɪd͡ʒ], \bɹˈɛkənɹˌɪdʒ], \b_ɹ_ˈɛ_k_ə_n_ɹ_ˌɪ_dʒ]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
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