BK8644
\bˌiːkˈe͡ɪ ˈe͡ɪt θˈa͡ʊzənd sˈɪkshˈʌndɹədən fˈɔːtifˈɔː], \bˌiːkˈeɪ ˈeɪt θˈaʊzənd sˈɪkshˈʌndɹədən fˈɔːtifˈɔː], \b_ˌiː_k_ˈeɪ ˈeɪ_t θ_ˈaʊ_z_ə_n_d s_ˈɪ_k_s_h_ˈʌ_n_d_ɹ_ə_d_ə_n f_ˈɔː_t_i_f_ˈɔː]\
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A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.