ADAMKIEWICZ'S TEST

\ˈadɐmkjˌuːɪkzɪz tˈɛst], \ˈadɐmkjˌuːɪkzɪz tˈɛst], \ˈa_d_ɐ_m_k_j_ˌuː_ɪ_k_z_ɪ_z t_ˈɛ_s_t]\

Definitions of ADAMKIEWICZ'S TEST

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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