SAPODILLA PLUM
\sˌapədˈɪlə plˈʌm], \sˌapədˈɪlə plˈʌm], \s_ˌa_p_ə_d_ˈɪ_l_ə p_l_ˈʌ_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.