QUININA (U.S.)
\kwˈɪnɪnə jˌuːˈɛs], \kwˈɪnɪnə jˌuːˈɛs], \k_w_ˈɪ_n_ɪ_n_ə__ j_ˌuː_ˈɛ_s]\
Definitions of QUININA (U.S.)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.