QUINIAE ARSENIS

\kwˈɪnɪˌiː ˈɑːsənˌiz], \kwˈɪnɪˌiː ˈɑːsənˌiz], \k_w_ˈɪ_n_ɪ__ˌiː_ ˈɑː_s_ə_n_ˌi_z]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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