PROXIMATE ANALYSIS

\pɹˈɒksɪmˌe͡ɪt ɐnˈaləsˌɪs], \pɹˈɒksɪmˌe‍ɪt ɐnˈaləsˌɪs], \p_ɹ_ˈɒ_k_s_ɪ_m_ˌeɪ_t ɐ_n_ˈa_l_ə_s_ˌɪ_s]\
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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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