PROTO ONCOGENE PRODUCTS BCL 2
\pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːn pɹˈɒdʌkts bˌiːsˌiːˈɛl tˈuː], \pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːn pɹˈɒdʌkts bˌiːsˌiːˈɛl tˈuː], \p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n p_ɹ_ˈɒ_d_ʌ_k_t_s b_ˌiː_s_ˌiː__ˈɛ_l t_ˈuː]\
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Membrane proteins encoded by the bcl-2 genes and serving as a potent inhibitor of cell death by apoptosis. The proteins are found on mitochondrial, microsomal, and nuclear membrane sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.