PACHYDERMIA LARYNGIS
\pat͡ʃˈa͡ɪdəmˌi͡ə lˈaɹɪŋɡˌiz], \patʃˈaɪdəmˌiə lˈaɹɪŋɡˌiz], \p_a_tʃ_ˈaɪ_d_ə_m_ˌiə l_ˈa_ɹ_ɪ_ŋ_ɡ_ˌi_z]\
Definitions of PACHYDERMIA LARYNGIS
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.