NEUROSPORA ENDONUCLEASE
\njˈuːɹəspˌɔːɹəɹ ˈɛndə͡ʊnjˌuːklɪˌe͡ɪs], \njˈuːɹəspˌɔːɹəɹ ˈɛndəʊnjˌuːklɪˌeɪs], \n_j_ˈuː_ɹ_ə_s_p_ˌɔː_ɹ_ə_ɹ ˈɛ_n_d_əʊ_n_j_ˌuː_k_l_ɪ__ˌeɪ_s]\
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An enzyme that catalyzes endonucleolytic cleavage to 5-phosphomononucleotides and 5-phosphooligonucleotide end-products. It has a preference for single-stranded substrates but is active with either ribo- or deoxyribonucleic acids. (From Enzyme Nomenclature, 1992) EC 3.1.30.1.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.