MISFORTUNATE

\mɪsfˈɔːt͡ʃənət], \mɪsfˈɔːt‍ʃənət], \m_ɪ_s_f_ˈɔː_tʃ_ə_n_ə_t]\

Definitions of MISFORTUNATE

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2006 - WordNet 3.0
By Princeton University

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  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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