LOCKIAN
\lˈɒki͡ən], \lˈɒkiən], \l_ˈɒ_k_iə_n]\
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lok'i-an, adj. pertaining to the philosophy of John Locke (1632-1704).--ns. LOCK'IAN, LOCK'IST.
By Thomas Davidson
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.