ISTHME DU GOSIER

\ˈɪsθm dˈuː ɡˈə͡ʊzɪə], \ˈɪsθm dˈuː ɡˈə‍ʊzɪə], \ˈɪ_s_θ_m d_ˈuː ɡ_ˈəʊ_z_ɪ__ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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