INVOLUCRUM CORDIS

\ɪnvˈɒlʌkɹəm kˈɔːdɪz], \ɪnvˈɒlʌkɹəm kˈɔːdɪz], \ɪ_n_v_ˈɒ_l_ʌ_k_ɹ_ə_m k_ˈɔː_d_ɪ_z]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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