IMPERATIVE CONCEPT
\ɪmpˈɛɹətˌɪv kˈɒnsɛpt], \ɪmpˈɛɹətˌɪv kˈɒnsɛpt], \ɪ_m_p_ˈɛ_ɹ_ə_t_ˌɪ_v k_ˈɒ_n_s_ɛ_p_t]\
Definitions of IMPERATIVE CONCEPT
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.