GROOVE, PRIMITIVE
\ɡɹˈuːv], \ɡɹˈuːv], \ɡ_ɹ_ˈuː_v]\
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Primitive streak or trace, Nota primitiva. A bright streak in the long axis of the pellucid part of the area germinativa, after it presents a central pellucid and a peripheral opake part, and passes from the round to the pear shape.
By Robley Dunglison
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.