GRIFFITH'S MIXTURE

\ɡɹˈɪfɪθz mˈɪkst͡ʃə], \ɡɹˈɪfɪθz mˈɪkst‍ʃə], \ɡ_ɹ_ˈɪ_f_ɪ_θ_z m_ˈɪ_k_s_tʃ_ə]\

Definitions of GRIFFITH'S MIXTURE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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