GOODPASTURE SYNDROME
\ɡˈʊdpast͡ʃə sˈɪndɹə͡ʊm], \ɡˈʊdpastʃə sˈɪndɹəʊm], \ɡ_ˈʊ_d_p_a_s_tʃ_ə s_ˈɪ_n_d_ɹ_əʊ_m]\
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A combination of pulmonary hemorrhage and glomerulonephritis. It is known also as the lung purpura glomerulonephritis complex. It is considered by some to be a form of hypersensitivity reaction.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.