GAYETANO ROSELL

\ɡˌe͡ɪɪtˈɑːnə͡ʊ ɹˈə͡ʊzə͡l], \ɡˌe‍ɪɪtˈɑːnə‍ʊ ɹˈə‍ʊzə‍l], \ɡ_ˌeɪ_ɪ_t_ˈɑː_n_əʊ ɹ_ˈəʊ_z_əl]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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