GANGOLPHE’S SIGN
\ɡˈaŋɡəlfˌɪz sˈa͡ɪn], \ɡˈaŋɡəlfˌɪz sˈaɪn], \ɡ_ˈa_ŋ_ɡ_ə_l_f_ˌɪ_z s_ˈaɪ_n]\
Definitions of GANGOLPHE’S SIGN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.