DENS SEROTINUS

\dˈɛnz sˈɛɹətˌɪnəs], \dˈɛnz sˈɛɹətˌɪnəs], \d_ˈɛ_n_z s_ˈɛ_ɹ_ə_t_ˌɪ_n_ə_s]\

Definitions of DENS SEROTINUS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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