COLOCYNTHINE

\kˈə͡ʊləsˌɪnθa͡ɪn], \kˈə‍ʊləsˌɪnθa‍ɪn], \k_ˈəʊ_l_ə_s_ˌɪ_n_θ_aɪ_n]\

Definitions of COLOCYNTHINE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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