CAPRIZANS PULSUS

\kˈapɹɪzənz pˈʌlsəs], \kˈapɹɪzənz pˈʌlsəs], \k_ˈa_p_ɹ_ɪ_z_ə_n_z p_ˈʌ_l_s_ə_s]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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