CACHECTIN TUMOR NECROSIS FACTOR
\kˈaʃɪktˌɪn tjˈuːmə nɛkɹˈə͡ʊsɪs fˈaktə], \kˈaʃɪktˌɪn tjˈuːmə nɛkɹˈəʊsɪs fˈaktə], \k_ˈa_ʃ_ɪ_k_t_ˌɪ_n t_j_ˈuː_m_ə n_ɛ_k_ɹ_ˈəʊ_s_ɪ_s f_ˈa_k_t_ə]\
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Serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share two receptors.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- cachectic fever
- cachectic infantilism
- cachectical
- cachectin
- cachectin receptors
- Cachectin Tumor Necrosis Factor
- cachelcoma
- cachemere
- cachemia
- cachen-laguen
- cachepot